Conclusion: Our findings suggest that illicit buprenorphine use is gaining ground primarily among whites and those who are more advanced in their drug use careers. Continued monitoring is needed to better understand evolving patterns and trends of illicit buprenorphine use. (Source: Drug and Alcohol Dependence)

Authors: Luo X, Trevejo J, van Heeswijk RP, Smith F, Garg V Abstract This was an open-label, single-sequence trial in HCV-negative volunteers on stable, individualized, buprenorphine maintenance therapy. Telaprevir 750mg every 8 hours was co-administered with buprenorphine/naloxone (4:1 ratio as sublingual tablets) for 7 days with food. Pharmacokinetic profiles of buprenorphine, norbuprenorphine and naloxone were […]

While regulatory controls on methadone clinics for opioid dependence resulted in treatment being physically and functionally isolated from conventional medical care, the delivery of an office-based treatment of buprenorphine and the buprenorphine/naloxone combination product over the last decade has facilitated the return of treatment to “mainstream medicine both for psychiatry and primary care.” (Source: Psychiatric […]

Conclusion Quality-improvement initiatives including staff education, incorporation of REMS requirements into existing policy, development of an electronic resource, and creation of a separate storage section for drugs subject to REMS were implemented at a large academic medical center to help ensure compliance with inpatient-applicable REMS requirements. PMID: 22555085 [PubMed – in process] (Source: American Journal […]