The Double-Edged Drug: At Clinics, Tumultuous Lives and Turbulent Care

November 18, 2013

The divided world of buprenorphine clinics serves as a crossroads where addicts’ tumultuous lives converge with a turbulent treatment environment.     (Source: NYT Health) MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.

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The Double-Edged Drug: In Demand in Clinics and on the Street, ‘Bupe’ Can Be Savior or Menace

November 17, 2013

High hopes for buprenorphine, an effective treatment for opioid addiction, have been tempered by a messy reality: health complications and deaths, unscrupulous doctors and a reputation as a street drug.     (Source: NYT Health)

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The Double-Edged Drug: Addiction Treatment With a Dark Side

November 17, 2013

High hopes for buprenorphine, an effective treatment for opioid addiction, have been tempered by a messy reality: health complications and deaths, unscrupulous doctors and a reputation as a street drug.     (Source: NYT Health) MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.

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Baseline characteristics and treatment outcomes in prescription opioid dependent patients with and without co-occurring psychiatric disorder.

November 15, 2013

Conclusions: Prescription opioid-dependent patients with a co-occurring psychiatric disorder had a better response to buprenorphine-naloxone treatment despite demonstrating greater impairment at baseline. Additional research is needed to determine the mechanism of this finding and to adapt treatments to address this population. PMID: 24219166 [PubMed – as supplied by publisher] (Source: The American Journal of Drug […]

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Advertising Drugs to Addicts

October 27, 2013

A glut of information about prescription drugs makes it easy for addicts to get their fix from doctors. But worst of all, celebrities are now the pushers.read more (Source: Psychology Today Addiction Center) MedWorm Sponsor Message: Have a look at The Addiction Daily, the new MedWorm portal, updated daily with all the latest addiction news […]

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The Reply

October 23, 2013

Although the article by Bowman et al did address the importance of naloxone prescription in primary care settings to prevent opioid overdoses in patients prescribed any opioid, the article did not address the prescribing of specific opioids for the treatment of chronic pain that could result in overdose. The focus of the article was on opioid addiction […]

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Clinician beliefs and attitudes about buprenorphine/naloxone diversion.

October 19, 2013

CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Attitudes and beliefs, not education level, were associated with clinician’s perceived danger from B/N diversion. Clinicians with greater B/N patient experience were more likely to believe treatment access barriers are the major cause of B/N diversion. (Am J Addict 2013;22:574-580). PMID: 24131165 [PubMed – in process] (Source: American Journal on Addictions) […]

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Parenteral buprenorphine-naloxone abuse is a major cause of fatal buprenorphine-related poisoning – Häkkinen M, Heikman P, Ojanperä I.

October 1, 2013

Buprenorphine (BPN) medication for opioid maintenance treatment in Finland consists predominantly of buprenorphine-naloxone (BNX). Both BPN and BNX are associated with diversion, abuse and non-medically supervised use worldwide. Our purpose was to estimate… (Source: SafetyLit: All (Unduplicated)) MedWorm Sponsor Message: Have a look at The Addiction Daily, the new MedWorm portal, updated daily with all […]

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Parenteral buprenorphine–naloxone abuse is a major cause of fatal buprenorphine-related poisoning

September 24, 2013

Abstract: Buprenorphine (BPN) medication for opioid maintenance treatment in Finland consists predominantly of buprenorphine–naloxone (BNX). Both BPN and BNX are associated with diversion, abuse and non-medically supervised use worldwide. Our purpose was to estimate the proportion of BNX to all BPN-related fatalities. The material consisted of 225 deceased drug abusers in Finland from January 2010 […]

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Longitudinal missing data strategies for substance use clinical trials using generalized estimating equations: an example with a buprenorphine trial

September 11, 2013

ConclusionsFuture researchers may find utilization of the MI procedure in conjunction with the common method of GEE analysis as a helpful analytic approach when the missing at random assumption is justifiable. Copyright © 2013 John Wiley & Sons, Ltd. (Source: Human Psychopharmacology: Clinical and Experimental) MedWorm Sponsor Message: Have a look at The Addiction Daily, […]

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