The relationship between primary prescription opioid and buprenorphine-naloxone induction outcomes in a prescription opioid dependent sample.

March 2, 2016

CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Difficult bup-nx inductions were not associated with participants’ primary PO. Severity of withdrawal, measured with the COWS, was an important variable, reminding clinicians that bup-nx should not be commenced prior to evidence of moderate opioid withdrawal. These findings add to the evidence that with careful procedures, bup-nx can used with few […]

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Parenteral buprenorphine-naloxone abuse is a major cause of fatal buprenorphine-related poisoning – Häkkinen M, Heikman P, Ojanperä I.

March 2, 2016

Buprenorphine (BPN) medication for opioid maintenance treatment in Finland consists predominantly of buprenorphine-naloxone (BNX). Both BPN and BNX are associated with diversion, abuse and non-medically supervised use worldwide. Our purpose was to estimate… (Source: SafetyLit: All (Unduplicated))

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Pharmaceutical and pharmacokinetic characterization of a novel sublingual buprenorphine/naloxone tablet formulation in healthy volunteers

March 2, 2016

Drug Development and Industrial Pharmacy, Ahead of Print. (Source: Drug Development and Industrial Pharmacy)

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Acute urinary retention secondary to buprenorphine administration

March 2, 2016

Urinary retention is associated with buprenorphine, particularly with epidural/intrathecal delivery. However, it is rare with oral administration. This case report illustrates an occurrence of acute urinary retention after initiation of oral buprenorphine/naloxone. (Source: The American Journal of Emergency Medicine)

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Clinician beliefs and attitudes about buprenorphine/naloxone diversion.

March 2, 2016

CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Attitudes and beliefs, not education level, were associated with clinician’s perceived danger from B/N diversion. Clinicians with greater B/N patient experience were more likely to believe treatment access barriers are the major cause of B/N diversion. (Am J Addict 2013;22:574-580). PMID: 24131165 [PubMed – in process] (Source: American Journal on Addictions)

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The Reply

March 2, 2016

Although the article by Bowman et al did address the importance of naloxone prescription in primary care settings to prevent opioid overdoses in patients prescribed any opioid, the article did not address the prescribing of specific opioids for the treatment of chronic pain that could result in overdose. The focus of the article was on opioid addiction […]

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Advertising Drugs to Addicts

March 2, 2016

A glut of information about prescription drugs makes it easy for addicts to get their fix from doctors. But worst of all, celebrities are now the pushers.read more (Source: Psychology Today Addiction Center)

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Baseline characteristics and treatment outcomes in prescription opioid dependent patients with and without co-occurring psychiatric disorder.

March 2, 2016

Conclusions: Prescription opioid-dependent patients with a co-occurring psychiatric disorder had a better response to buprenorphine-naloxone treatment despite demonstrating greater impairment at baseline. Additional research is needed to determine the mechanism of this finding and to adapt treatments to address this population. PMID: 24219166 [PubMed – as supplied by publisher] (Source: The American Journal of Drug […]

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Mind Meets Body: Developing a Psychology Internship in a Family Medicine Residency Program (Raymond Hornyak PhD)

March 2, 2016

Mind Meets Body: Creating a Primary Care Psychology Internship in a Family Medicine Residency Program Introduction: Multiple studies have identified the benefits of providing behavioral health services to primary care patients. Decreased length of stay, fewer hospitalizations and emergency room visits, less frequent office visits, fewer prescriptions, and improvement in health outcomes have been associated […]

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The Double-Edged Drug: In Demand in Clinics and on the Street, ‘Bupe’ Can Be Savior or Menace

March 2, 2016

High hopes for buprenorphine, an effective treatment for opioid addiction, have been tempered by a messy reality: health complications and deaths, unscrupulous doctors and a reputation as a street drug.     (Source: NYT Health)

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