Buprenorphine therapy: an increasing challenge in oral and maxillofacial surgery

March 2, 2016

Suboxone is a 4:1 mixture of buprenorphine and naloxone and Subutex is buprenorphine alone. The high affinity μ-receptor binding of buprenorphine (Suboxone and Subutex) renders other opioids ineffective. Inadequate procedural sedation, inadequate analgesia, and significant drug interactions complicate the treatment of patients taking Suboxone or Subutex. Careful planning and an understanding of buprenorphine pharmacology can […]

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Zubsolv (Buprenorphine and Naloxone Sublingual Tablets) – new on RxList

March 2, 2016

(Source: RxList – New and Updated Drug Monographs)

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Zubsolv (Buprenorphine and Naloxone) – Maintenance Treatment for Opioid Dependence

March 2, 2016

Zubsolv (buprenorphine and naloxone) is a sublingual tablet indicated as maintenance treatment for people suffering from opioid dependence. (Source: Drug Development Technology)

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Methadone and buprenorphine-naloxone are effective in reducing illicit buprenorphine and other opioid use, and reducing HIV risk behavior—Outcomes of a randomized trial

March 2, 2016

Conclusions: Daily observed methadone or buprenorphine-naloxone are effective treatments for non-medical buprenorphine and other opioid use in the Republic of Georgia and likely to be useful for preventing HIV infection. (Source: Drug and Alcohol Dependence)

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Buprenorphine Implants for Treatment of Opioid Dependence: Randomized Comparison to Placebo and Sublingual Buprenorphine/Naloxone

March 2, 2016

ConclusionsCompared with placebo, buprenorphine implants result in significantly less frequent opioid use, and are non‐inferior to sublingual buprenorphine/naloxone tablets. (Source: Addiction)

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Treatment Retention among Patients Randomized to Buprenorphine/Naloxone Compared to Methadone in A Multi‐site Trial

March 2, 2016

ConclusionsProvision of methadone appears to be associated with better retention in treatment for opioid dependence than buprenorphine, as does use of provision of higher doses of both medications. Provision of buprenorphine is associated with lower continued use of illicit opioids. (Source: Addiction) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find […]

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Table of Contents

March 2, 2016

Abstract CDC and NIDA Tout PrEP for HIV‐Negative Injecting Drug Users Monitor Vendor Protocols when Signing up for Drug Testing AAP OKs Breastfeeding on Methadone but Not Buprenorphine ONDCP and SAMHSA Release Opioid Toolkit, Promote Naloxone SAMHSA Releases Draft Outcome Measures, Gives 9/17 Deadline for Feedback DOJ to Allow Marijuana Ballot Initiatives to Go Forward […]

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Root Causes, Clinical Effects, and Outcomes of Unintentional Exposures to Buprenorphine by Young Children

March 2, 2016

Conclusions: Unintentional exposure to buprenorphine can cause central nervous system depression, respiratory depression, and death in young children. Exposure rates to film formulations are significantly less than to tablet formulations. Package and storage deficiencies contribute to unintentional exposures in young children. (Source: The Journal of Pediatrics)

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Longitudinal missing data strategies for substance use clinical trials using generalized estimating equations: an example with a buprenorphine trial

March 2, 2016

ConclusionsFuture researchers may find utilization of the MI procedure in conjunction with the common method of GEE analysis as a helpful analytic approach when the missing at random assumption is justifiable. Copyright © 2013 John Wiley & Sons, Ltd. (Source: Human Psychopharmacology: Clinical and Experimental)

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Parenteral buprenorphine–naloxone abuse is a major cause of fatal buprenorphine-related poisoning

March 2, 2016

Abstract: Buprenorphine (BPN) medication for opioid maintenance treatment in Finland consists predominantly of buprenorphine–naloxone (BNX). Both BPN and BNX are associated with diversion, abuse and non-medically supervised use worldwide. Our purpose was to estimate the proportion of BNX to all BPN-related fatalities. The material consisted of 225 deceased drug abusers in Finland from January 2010 […]

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