Non-Analgesic Effects of Opioids: Opioid-induced Respiratory Depression.

March 2, 2016

Authors: Boom M, Niesters M, Sarton E, Aarts L, Smith TW, Dahan A Abstract Opioids induce respiratory depression via activation of µ-opioid receptors at specific sites in the central nervous system including the pre-Bötzinger complex, a respiratory rhythm generating area in the pons. Full opioid agonists like morphine and fentanyl affect breathing with onset and […]

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Conversion of chronic pain patients from full-opioid agonists to sublingual buprenorphine.

March 2, 2016

CONCLUSIONS: Patients continuing buprenorphine SL therapy for more than 60 days reported significant decreases in pain (2.3 points). Patients on doses of opioid medication between 100-199 mg morphine equivalents seemed to fare better with conversion to buprenorphine SL than patients on the highest doses (> 400 mg morphine equivalents). The opioid drug used by the […]

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Office-based opioid dependence treatment.

March 2, 2016

CONCLUSION: Opioid dependency, whether it results from the misuse or abuse of prescription or street drugs, continues to be a significant public health issue. Passage of DATA 2000 and US Food and Drug Administration approval of buprenorphine and buprenorphine/ naloxone has revolutionized opioid dependence therapy. The traditional addiction medicine therapy regimen of methadone maintenance, with […]

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Table of Contents

March 2, 2016

AbstractSupreme Court Upholds Individual Mandate, Medicaid ExpansionProgram Blends Suboxone and Alternative Addiction TreatmentsSAAS/NIATx Attendees Learn How to Function Like BusinessesNew WHO Database Maps Addiction Resources in 147 CountriesNational Organization Setting Standards for Recovery HomesWest Virginia AG Sues 14 Rx Drug DistributorsMeeting Coverage for NASADAD and RSABriefly NotedNames in the NewsComing up (Source: Alcoholism and Drug […]

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Predictors of attrition with buprenorphine/naloxone treatment in opioid dependent youth.

March 2, 2016

CONCLUSIONS: Prompt attention to those with early non-adherence to medication or an early opioid positive urine, markers available in the first 2weeks of treatment, may improve treatment retention. Extended Bup/Nal treatment appeared effective in improving treatment retention for youth with opioid dependence across a wide range of demographics, and pre-treatment clinical characteristics. PMID: 22626890 [PubMed […]

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Buprenorphine/Naloxone and dental caries: a case report.

March 2, 2016

Authors: Suzuki J, Park EM PMID: 22882403 [PubMed – in process] (Source: American Journal on Addictions)

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Course and treatment of buprenorphine/naloxone withdrawal: an analysis of case reports.

March 2, 2016

Authors: Westermeyer J, McCance-Katz EF Abstract Currently published information on buprenorphinenaloxone withdrawal recommends a gradually decreasing dosage over weeks to months. In this case report, abrupt cessation of buprenorphine/naloxone at various doses, and after variable durations of treatment, resulted in mild opiate withdrawal lasting over approximately 1-2 days that did not require additional opioid medication […]

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Reckitt Benckiser Pharmaceuticals Inc. Announces FDA Approval of Two New Dosage Strengths of Suboxone Sublingual Film (C-III) for Maintenance Treatment of Opioid Dependence

March 2, 2016

RICHMOND, Va., Aug. 20, 2012 /PRNewswire/ — Reckitt Benckiser Pharmaceuticals Inc. today announced the U.S. Food and Drug Administration (FDA) approval of the 4 mg and 12 mg doses of Suboxone® (buprenorphine and naloxone) sublingual… (Source: Drugs.com – Pharma News)

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Reckitt Benckiser Pharmaceuticals Inc. Announces FDA Approval of Two New Dosage Strengths of Suboxone(R) Sublingual Film (C-III) for Maintenance Treatment of Opioid Dependence

March 2, 2016

RICHMOND, Va., Aug. 20, 2012 (HSMN NewsFeed) — Reckitt Benckiser Pharmaceuticals Inc. today announced the U.S. Food and Drug Administration (FDA) approval of the 4 mg and 12 mg doses of Suboxone® (buprenorphine and naloxone) sublingual film. Suboxon… Biopharmaceuticals, FDAReckitt Benckiser, Suboxone, buprenorphine, naloxone (Source: HSMN NewsFeed)

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SUBOXONE (Buprenorphine Hydrochloride, Naloxone Hydrochloride) Film, Soluble [Reckitt Benckiser Pharmaceuticals Inc]

March 2, 2016

Updated Date: Aug 30, 2012 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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