Buprenorphine/naloxone/neuropsychotherapeutics interaction: Obtundation: case report

March 2, 2016

(Source: Reactions)

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Missing data in substance abuse treatment research: Current methods and modern approaches.

March 2, 2016

This study demonstrates that the researcher can obtain markedly different results depending on how the missing data are handled. Missing data theory suggests that listwise deletion and single imputation procedures should not be used to account for missing information, and that MI has advantages with respect to internal and external validity when the assumption of […]

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Illicit use of buprenorphine in a community sample of young adult non-medical users of pharmaceutical opioids

March 2, 2016

Conclusion: Our findings suggest that illicit buprenorphine use is gaining ground primarily among whites and those who are more advanced in their drug use careers. Continued monitoring is needed to better understand evolving patterns and trends of illicit buprenorphine use. (Source: Drug and Alcohol Dependence)

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The Effect of Telaprevir on the Pharmacokinetics of Buprenorphine in Volunteers on Stable Buprenorphine/Naloxone Maintenance Therapy.

March 2, 2016

Authors: Luo X, Trevejo J, van Heeswijk RP, Smith F, Garg V Abstract This was an open-label, single-sequence trial in HCV-negative volunteers on stable, individualized, buprenorphine maintenance therapy. Telaprevir 750mg every 8 hours was co-administered with buprenorphine/naloxone (4:1 ratio as sublingual tablets) for 7 days with food. Pharmacokinetic profiles of buprenorphine, norbuprenorphine and naloxone were […]

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Update on Opioid Dependence and Its Treatment

March 2, 2016

While regulatory controls on methadone clinics for opioid dependence resulted in treatment being physically and functionally isolated from conventional medical care, the delivery of an office-based treatment of buprenorphine and the buprenorphine/naloxone combination product over the last decade has facilitated the return of treatment to “mainstream medicine both for psychiatry and primary care.” (Source: Psychiatric […]

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Risk evaluation and mitigation strategies: Assessment of a medical center's policies and procedures.

March 2, 2016

Conclusion Quality-improvement initiatives including staff education, incorporation of REMS requirements into existing policy, development of an electronic resource, and creation of a separate storage section for drugs subject to REMS were implemented at a large academic medical center to help ensure compliance with inpatient-applicable REMS requirements. PMID: 22555085 [PubMed – in process] (Source: American Journal […]

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Agonist-selective effects of opioid receptor ligands on cytosolic calcium concentration in rat striatal neurons

March 2, 2016

Conclusions: Our results suggest that buprenorphine and β-endorphin act on a distinct type/subtype of plasmalemmal opioid receptors or activate intracellular opioid-like receptor(s) in rat striatal neurons. (Source: Drug and Alcohol Dependence) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

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SUBOXONE (Buprenorphine Hydrochloride, Naloxone Hydrochloride) Tablet [Lake Erie Medical Surgical Supply DBA Quality Care Products LLC]

March 2, 2016

Updated Date: May 31, 2012 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Evaluation of Buprenorphine Dosage Adequacy in Opioid Receptor Agonist Substitution Therapy for Heroin Dependence: First Use of the Buprenorphine-Naloxone Dosage Adequacy Evaluation (BUDAVA) Questionnaire

March 2, 2016

(Source: Clinical Drug Investigation)

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Medically assisted recovery from opiate dependence within the context of the UK drug strategy: Methadone and Suboxone (buprenorphine–naloxone) patients compared

March 2, 2016

This article describes a small, naturalistic comparison of the efficacy of the two most commonly prescribed opiate substitute medications in the UK—methadone hydrochloride (methadone oral solution) and Suboxone (buprenorphine–naloxone sublingual tablets)—for reducing current heroin users’ (n=34) days of heroin use, and preventing short-term abstainers (n=37) from relapsing to regular heroin use. All patients had been […]

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