Abuse and diversion of buprenorphine sublingual tablets and film

March 2, 2016

Abstract: Buprenorphine abuse is common worldwide. Rates of abuse and diversion of three sublingual buprenorphine formulations (single ingredient tablets; naloxone combination tablets and film) were compared. Data were obtained from the Researched Abuse, Diversion, and Addiction-Related Surveillance (RADARS®) System Poison Center, Drug Diversion, Opioid Treatment (OTP), Survey of Key Informants’ Patients (SKIP), and College Survey […]

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Barriers to primary care physicians prescribing of buprenorphine for opioid addiction

March 2, 2016

Buprenorphine-naloxone is a highly effective outpatient treatment for opioid addiction, yet few physicians offer it. Researchers in Washington State examine barriers to prescribing buprenorphine among physicians who have been trained in its use, and they find that a lack of mental health and psychosocial support, time constraints, and a lack of specialty, institutional and partner […]

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Millennium Treatment Group Now Prescribing Suboxone for Detox

March 2, 2016

Suboxone has become a popular medication to use in detox from alcohol and other opiate addictions.(PRWeb March 14, 2014)Read the full story at http://www.prweb.com/releases/2014/03/prweb11671625.htm (Source: PRWeb: Medical Pharmaceuticals)

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Abuse and diversion of buprenorphine sublingual tablets and film – Lavonas EJ, Severtson SG, Martinez EM, Bucher-Bartelson B, Le Lait MC, Green JL, Murrelle LE, Cicero TJ, Kurtz SP, Rosenblum A, Surratt HL, Dart RC.

March 2, 2016

Buprenorphine abuse is common worldwide. Rates of abuse and diversion of three sublingual buprenorphine formulations (single ingredient tablets; naloxone combination tablets and film) were compared. Data were obtained from the Researched Abuse, Diversion, … (Source: SafetyLit: All (Unduplicated))

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Respiratory effects of buprenorphine/naloxone alone and in combination with diazepam in naive and tolerant rats.

March 2, 2016

In conclusion, differences in respiratory effects between BUP/NLX and BUP are only significant in combination with DZP, with increased depression in naive rats but reduced depression in in BUP-tolerant rats. However, BUP/NLX benefits in humans remain to be determined. PMID: 24769261 [PubMed – as supplied by publisher] (Source: Toxicology Letters)

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Behavioural treatment combined with buprenorphine does not reduce opioid use compared with buprenorphine alone

March 2, 2016

Question Question: In the treatment of opioid dependence, does the addition of behavioural treatment to buprenorphine reduce opioid use compared with buprenorphine alone? Patients: In total, 202 people meeting Diagnostic and Statistical Manual of Mental Disorders, 4th edition, Text Revised (DSM-IV-TR) criteria for opioid dependence. Participants had to have good general medical and psychiatric health, […]

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Detoxification treatments for opiate dependent adolescents.

March 2, 2016

CONCLUSIONS: It is difficult to draw conclusions on the basis of two trials with few participants. Furthermore, the two studies included did not consider the efficacy of methadone that is still the most frequent drug utilised for the treatment of opioid withdrawal. One possible reason for the lack of evidence could be the difficulty in […]

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Potentiation of the effect of buprenorphine/naloxone with gabapentin or quetiapine.

March 2, 2016

Authors: Reeves RR, Ladner ME PMID: 24880512 [PubMed – in process] (Source: The American Journal of Psychiatry)

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The Impact of Prior Authorization on Buprenorphine Dose, Relapse Rates, and Cost for Massachusetts Medicaid Beneficiaries with Opioid Dependence

March 2, 2016

ConclusionPrior authorization policies strategically targeted by dose level appear to successfully reduce use of higher than recommended buprenorphine doses. Savings from these policies are modest and may be accompanied by brief increases in relapse rates. Lower doses may decrease diversion of buprenorphine. (Source: Health Services Research)

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BUPRENORPHINE HYDROCHLORIDE AND NALOXONE HYDROCHLORIDE DIHYDRATE Tablet [Actavis Elizabeth LLC]

March 2, 2016

Updated Date: Jun 6, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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