A Prospective, Randomized, Multicenter Acceptability And Safety Study Of Direct Buprenorphine/Naloxone Induction In Heroin‐Dependent Individuals

March 2, 2016

Conclusions:  Direct BNX induction was a safe and effective strategy for maintenance treatment of opioid dependence. Response to high‐dose direct BNX induction appears to be similar to indirect BPN‐to‐BNX induction and was not associated with reports of intravenous BNX misuse. (Source: Addiction)

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SUBOXONE (Buprenorphine Hydrochloride And Naloxone Hydrochloride) Tablet [Bryant Ranch Prepack]

March 2, 2016

Updated Date: Jul 14, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST)) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

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SUBOXONE (Buprenorphine And Naloxone) Film, Soluble [Bryant Ranch Prepack]

March 2, 2016

Updated Date: Jul 15, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Addiction Drug Saves Medicaid Dollars in Long Run (CME/CE)

March 2, 2016

(MedPage Today) — Giving Medicaid patients with substance abuse problems access to buprenorphine (Subutex, Suboxone) is ultimately less expensive than maintaning them on methadone, the experience in one state showed. (Source: MedPage Today Psychiatry)

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How Is Suboxone Treatment Different than Drug Abuse?

March 2, 2016

Physicians who treat opioid addiction also have the option of utilizing ‘medication-assisted treatment,’ and the most common medications used in the treatment of opioid dependence today are methadone, naltrexone, and buprenorphine (Suboxone). Most people cannot just walk away from opioid addiction. They need help to change their thinking, behavior, and environment. Unfortunately, “quitting cold turkey” […]

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Short-term safety of buprenorphine/naloxone in HIV-seronegative opioid-dependent Chinese and Thai drug injectors enrolled in HIV Prevention Trials Network 058

March 2, 2016

Conclusions: In Chinese and Thai opioid-dependent injectors, we found BUP/NX to be effective in reducing opioid withdrawal symptoms and safe during short-term use. ALT increases were observed over 4-week-follow-up, which are consistent with reports from Western populations. Long-term safety and efficacy evaluations are indicated. (Source: International Journal of Drug Policy)

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Combined liquid chromatography-coulometric detection and microextraction by packed sorbent for the plasma analysis of long acting opioids in heroin addicted patients.

March 2, 2016

Authors: Somaini L, Saracino MA, Marcheselli C, Zanchini S, Gerra G, Raggi MA Abstract The sublingual combination of buprenorphine and naloxone (Suboxone(®)) and Methadone Maintenance Therapy have been found effective in treating heroin addiction. A new analytical method suitable for the simultaneous determination of buprenorphine, norbuprenorphine, methadone and naloxone in human plasma by means of […]

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CADTH Rapid Response Report: Clinical evidence for Suboxone® (buprenorphine/naloxone) for short-term detoxification

March 2, 2016

Source: Canadian Agency for Drugs and Technologies in Health (CADTH) Area: News This Rapid Response Report from the Canadian Agency for Drugs and Technologies in Health (CADTH) discusses the available evidence regarding the comparative clinical efficacy and safety of short term (<4 weeks) use of Suboxone® (buprenorphine/naloxone) compared with other opioid detoxification agents such as […]

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Escitalopram is associated with reductions in pain severity and pain interference in opioid dependent patients with depressive symptoms

March 2, 2016

Summary: Use of escitalopram 10mg daily compared to placebo resulted in decreased pain severity and interference in a sample of opioid-dependent patients with depressive symptoms.Abstract: Pain is common among opioid-dependent patients, yet pharmacologic strategies are limited. The aim of this study was to explore whether escitalopram, a selective serotonin reuptake inhibitor, was associated with reductions […]

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Compensation Effects on Clinical Trial Data Collection in Opioid-Dependent Young Adults.

March 2, 2016

Conclusion: These findings suggest that variations in the amount of compensation for completing assessments can differentially affect outcome measurements, depending on treatment group assignment. Scientific Significance: Adequate financial compensation may minimize bias when treatment condition is associated with differential dropout and may be a cost-effective way to reduce attrition. Moreover, active users may be more […]

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